Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation

Status: Recruiting
Location: See location...
Intervention Type: Combination product
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY

This study plans to learn more about using contrast enhanced ultrasound (CEUS) in brain tumor surgery. The goal of glioma brain tumor surgery is to remove as much of the glioma as possible. Tumor tissue that is close to normal brain tissue can look very similar. This can make it difficult for the surgeon to remove all the tumor. In this study, we hope to learn if using CEUS during brain tumor surgery will allow the brain surgeon to better see and remove all the tumor tissue.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 95
Healthy Volunteers: f
View:

• Able to sign and date the consent form

• Stated willingness to comply with all study procedures and be available for the duration of the study

• Be a male or female aged 18-95

• Have a planned standard of care surgery for presumed primary or known recurrent glioma

• WHO performance status \</= 2 (equivalent Karnofsky Performance Status, KPS\>/= 70)

• Patient of childbearing potential must have a negative pregnancy test within 14 days of inclusion

Locations
United States
Colorado
University of Colorado Anschutz Medical Campus
RECRUITING
Aurora
Contact Information
Primary
Jen Maitlen, BSN
jennifer.maitlen@cuanschutz.edu
303-724-1995
Backup
Terra Ornelas, BSN
terra.ornelas@cuanschutz.edu
303-724-7970
Time Frame
Start Date: 2025-12-01
Estimated Completion Date: 2027-06
Participants
Target number of participants: 100
Treatments
Experimental: Brain tumor surgery with Definity contrast and Contrast Enhanced Ultrasound
Related Therapeutic Areas
Sponsors
Leads: University of Colorado, Denver

This content was sourced from clinicaltrials.gov